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Avantor® Bridgewater Innovation Center

Capabilities that power science at every step

Process development scientist in cell and gene therapy lab.

With full upstream, downstream, and analytical capabilities, the C> labs produce AAV vectors to support the development and evaluation of next-generation reagents, purification techniques, and analytical methods, driving innovation from concept to practice.

Researcher preparing a cell culture bioreactor

In the fermentation lab, scientists and bioprocessing specialists focus on recombinant ligand design to improve purification processes for mAbs, bispecific antibodies, and vector production.

The cell culture lab focuses on advanced cell line development for biotherapeutic production, as well as creating new reagents, supplements and pump systems to optimize upstream workflows.

Downstream development engineers optimize a chromatography process.

The downstream processing lab develops new solutions for the efficient purification of mAbs, recombinant proteins, and plasmid DNA for cell and gene therapy applications. Leveraging deep expertise in a range of purification techniques, the labs also collaborate with customers to simulate their bioprocess workflows to streamline production, solve bottlenecks and identify tailored strategies to optimize the use of Avantor products.

Technician in cleanroom using advanced biologic analytical tools

The analytical lab focuses on the testing and measurement of Avantor products to ensure quality and safety. The chemistry and material science lab specializes in creating new materials through the chemistry and material synthesis of new chemicals, peptides and chromatography resins. The labs also focus on purifying existing products to higher grades.

Buffer production and cell culture media prep in the pilot plant

The fully equipped buffer preparation lab enables Avantor to optimize single-use powder and liquid material preparation, accelerate scale-up of new products and processes, and automate production with single-use technologies.

The buffer prep team collaborates with the pilot scale upstream and downstream labs to make and deliver buffers for critical operations, including mammalian cell culture, fermentation, chromatography and fill-finish.

Technician working in pilot plant production area

The Class 10 cleanroom and chemical kilo labs serve as manufacturing suites for specialty materials such as novel chromatography resins and excipient-grade products such as our J.T.Baker® cell lysis and viral inactivation solutions that require aseptic filling in closed operations. These labs leverage key Avantor bioprocessing technologies to achieve the tight tolerances required during fluid handling and dispensing operations, including single-use assemblies, mixing systems and Masterflex® pumps.

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Quality is an essential element of every process, product and solution at Avantor and is the foundation for the value we deliver every day.

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Our innovation and technology center in Suwon, South Korea, focuses on optimizing purification processes for biopharmaceuticals.

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Our technology-driven research and collaboration center in Shanghai, China, advances biopharma in the AMEA region, optimizing process efficiency for monoclonal antibodies and engineering vaccines to improve global health.

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Our leading experts discuss innovation, process solutions, industry trends and more to drive progress on life-saving therapies.